A Rare Presentation: Leptomeningeal Disease Involving the Left Cerebellar Hemisphere and Lumbosacral Region in Breast Cancer

Leptomeningeal disease (LMD) is a rare condition that occurs in fewer than 5% of breast cancer patients. In certain instances, individuals exhibit symptoms of LMD when initially diagnosed. We present a case involving a 48-year-old female who experienced a sudden onset of weakness in her left upper and lower limbs, leading to an extensive LMD diagnosis. A series of investigations were initiated to uncover the root cause of LMD. Subsequent MRI scans covering both the entire brain and the spinal cord confirmed the presence of metastatic breast carcinoma, thus providing insight into the origin of her condition. Following this, the patient underwent a regimen of radiation therapy to address the metastases and then started a comprehensive neuro-rehabilitation program aimed at improving her overall well-being and quality of life.