Harbin Medical University Researchers Add New Data to Research in Idiopathic Pulmonary Fibrosis (Up-regulated SPP1 increases the risk from IPF to lung cancer via activating the pro-tumor macrophages).
In: Cancer Weekly, 2023-12-12, S. 343-343
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Zugriff:
Researchers from Harbin Medical University in China have conducted a study to investigate the pathogenesis of lung cancer (LC) in patients with idiopathic pulmonary fibrosis (IPF) and develop a predictor for detecting IPF patients at risk for LC. The study identified 42 common immune function-related pathogenic genes between IPF and LC and developed a five-gene classifier that can successfully distinguish high-risk IPF patients. The study also revealed that SPP1+ macrophages may promote the progression from IPF to LC and highlighted SPP1 as a critical driver in IPF progression, offering a potential target for therapy in fibrosis. [Extracted from the article]
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Titel: |
Harbin Medical University Researchers Add New Data to Research in Idiopathic Pulmonary Fibrosis (Up-regulated SPP1 increases the risk from IPF to lung cancer via activating the pro-tumor macrophages).
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Zeitschrift: | Cancer Weekly, 2023-12-12, S. 343-343 |
Veröffentlichung: | 2023 |
Medientyp: | serialPeriodical |
ISSN: | 1071-7218 (print) |
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