Patent Issued for Optimized antibodies that target CD19 (USPTO 11618788).
In: Clinical Trials Week, 2023-04-24, S. 510-510
serialPeriodical
Zugriff:
The stages of B-cell development include Progenitor B cells, Early Pro-B cells, Late Pro-B cells, Large Pre-B cells, Small Pre-B cells, Immature B cells, and Mature B cells. "In one aspect, the invention is directed to antibody that binds CD19, including at least one modification in the constant region relative to a parent anti-CD19 antibody, wherein the antibody binds with increased affinity to the FcgRIIIa receptor as compared to the parent antibody. "Plasma B cells (also known as plasma cells) are large B cells that have been exposed to antigen and produce and secrete large amounts of antibodies, which assist in the destruction of microbes by binding and facilitating targeting by phagocytes, as well as activation of the complement system. [Extracted from the article]
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Patent Issued for Optimized antibodies that target CD19 (USPTO 11618788).
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Zeitschrift: | Clinical Trials Week, 2023-04-24, S. 510-510 |
Veröffentlichung: | 2023 |
Medientyp: | serialPeriodical |
ISSN: | 1543-6772 (print) |
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