Characterization of Cationic Modified Debranched Starch and Formation of Complex Nanoparticles with κ-Carrageenan and Low Methoxyl Pectin.

Liu, Q ; Li, M ; et al.

In: Journal of agricultural and food chemistry, Jg. 67 (2019-03-13), Heft 10, S. 2906-2915

academicJournal

The functional modifications of debranched starch (DBS) has been attracting the interest of researchers. This study marks the first time that DBS was modified by cationization through the use of (3-chloro-2-hydroxypropyl) trimethylammonium chloride with the introduction of cationic functional groups. The physicochemical properties and structural characteristics of cationized debranched starch (CDBS) were systematically assessed. The results demonstrate that the maximum degree of substitution (DS) value obtained was as high as 1.14, and the corresponding CDBS exhibited significantly higher zeta potential values: approximately +35 mV. The minimal inhibitory concentration values of the CDBS of DS 1.14 against Escherichia coli and Staphylococcus aureus were 6 and 8 mg mL -1 , respectively. In addition, nanoparticles were successfully prepared with a combination of CDBS and low methoxyl pectin (LMP) and a combination of CDBS and κ-carrageenan (CRG). The maximum encapsulation efficiency of nanoparticles for (-)-epigallocatechingallate can reach 87.8%.

Titel:	Characterization of Cationic Modified Debranched Starch and Formation of Complex Nanoparticles with κ-Carrageenan and Low Methoxyl Pectin.
Autor/in / Beteiligte Person:	Liu, Q ; Li, M ; Xiong, L ; Qiu, L ; Bian, X ; Sun, C ; Sun, Q
Zeitschrift:	Journal of agricultural and food chemistry, Jg. 67 (2019-03-13), Heft 10, S. 2906-2915
Veröffentlichung:	Washington, American Chemical Society., 2019
Medientyp:	academicJournal
ISSN:	1520-5118 (electronic)
DOI:	10.1021/acs.jafc.8b05045
Schlagwort:	Anti-Bacterial Agents pharmacology Catechin analogs & derivatives Catechin chemistry Staphylococcus aureus drug effects Staphylococcus aureus growth & development Starch pharmacology Anti-Bacterial Agents chemistry Carrageenan chemistry Cations chemistry Drug Carriers chemistry Nanoparticles chemistry Pectins chemistry Starch chemistry
Sonstiges:	Nachgewiesen in: MEDLINE Sprachen: English Publication Type: Journal Article Language: English [J Agric Food Chem] 2019 Mar 13; Vol. 67 (10), pp. 2906-2915. <i>Date of Electronic Publication: </i>2019 Feb 27. MeSH Terms: Anti-Bacterial Agents / chemistry ; Carrageenan / chemistry ; Cations / chemistry ; Drug Carriers / chemistry ; Nanoparticles / chemistry ; Pectins / chemistry ; Starch / *chemistry ; Anti-Bacterial Agents / pharmacology ; Catechin / analogs & derivatives ; Catechin / chemistry ; Staphylococcus aureus / drug effects ; Staphylococcus aureus / growth & development ; Starch / pharmacology Contributed Indexing: Keywords: antibacterial activity; electrostatic interaction; functionality; short chain amylose Substance Nomenclature: 0 (Anti-Bacterial Agents) ; 0 (Cations) ; 0 (Drug Carriers) ; 89NA02M4RX (Pectins) ; 8R1V1STN48 (Catechin) ; 9000-07-1 (Carrageenan) ; 9005-25-8 (Starch) ; BQM438CTEL (epigallocatechin gallate) Entry Date(s): Date Created: 20190222 Date Completed: 20190322 Latest Revision: 20190322 Update Code: 20231215

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