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Spinodal Crystallization of Polymers: Crystallization from the Unstable Melt
This paper reviews the authors' investigation into polymer crystallization, especially involving a spinodal decomposition (SD) type phase...
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PEGylation of Proteins as Tailored Chemistry for Optimized Bioconjugates
The high potential of peptides and proteins as therapeutic agents has not been fully exploited because of their common shortcomings: the only...
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Polymer Therapeutics for Cancer: Current Status and Future Challenges
Drug delivery systems for cancer therapeutics have revolutionized medicine. Delivery systems have improved the efficacy and reduced the toxicity of...
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Enzymatic Polymerization to Polysaccharides
Polysaccharides are formed by repeated glycosylations between a sugar donor and a sugar acceptor. This chapter reviews the in vitro synthesis of...
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Polymer Therapeutics: Polymers as Drugs, Drug and Protein Conjugates and Gene Delivery Systems: Past, Present and Future Opportunities
As the 21st century begins we are witnessing a paradigm shift in medical practice. Whereas the use of polymers in biomedical materials applications...
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Block Copolymer Micelles
This review summarizes recent advances to date in the area of block copolymer micelles and also tries to highlight some new directions in that...
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Surface-Grafted Polymer Gradients: Formation, Characterization, and Applications
This review presents to-date progress in the formation of surface-tethered polymer assemblies with gradually varying physico-chemical properties....
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Computer-Aided Conformation-Dependent Design of Copolymer Sequences
A survey is given of the simulation methods as applied to the design of nontrivial sequences in synthetic copolymers aimed at achieving desired...
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After-Action of the Ideas of I.M. Lifshitz in Polymer and Biopolymer Physics
We review the development of ideas in polymer physics initially formulated by I.M. Lifshitz. We start with general issues in polymer statistics,...
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Role of Physical Factors in the Process of Obtaining Copolymers
A brief introduction into the principles of the statistical description of the chemical structure of linear heteropolymers is given....
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Polypeptide and Polypeptide Hybrid Copolymer Synthesis via NCA Polymerization
This article summarizes recent developments in the synthesis of polypeptides and hybrid peptide copolymers. Traditional methods used to polymerize...
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Nucleation and Crystallization in Diblock and Triblock Copolymers
Crystallization of block copolymer microdomains can have a tremendous influence on the morphology, properties and applications of these materials....
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Molecular Dynamics Modeling of the Crystal-Melt Interfaces and the Growth of Chain Folded Lamellae
The molecular mechanism of polymer crystallization is one of the most difficult problems and has defied innumerable efforts to understand the...
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Gene Delivery Using Polymer Therapeutics
The use of polymers as synthetic non-viral carriers for introducing nucleic acids into cells appears very appealing. Polymers can be generated in...
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Topological Mechanism of Polymer Nucleation and Growth – The Role of Chain Sliding Diffusion and Entanglement
Direct evidence of nucleation during the induction period of nucleation from the melt is obtained for the first time by means of small angle X-ray...
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Synthesis of Phenol Polymers Using Peroxidases
This chapter deals with the peroxidase-catalyzed polymerization of phenol and its derivatives. Such a polymerization needs an oxidation reagent,...
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Modeling Polymer Crystallization
We summarize the salient conclusions derived from Langevin dynamics simulations of many flexible polymer molecules undergoing crystallization from...
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Polymer Brushes by Anionic and Cationic Surface-Initiated Polymerization (SIP)
The formation of homopolymer and block copolymer brushes grafted from flat and nanoparticle surfaces via surface-initiated anionic and cationic...
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Solution Properties of Polypeptide-based Copolymers
The aggregation behaviour of biomimetic polypeptide hybrid copolymers and copolypeptides is here reviewed with a particular eye on the occurrence...
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Nanostructured Devices Based on Block Copolymer Assemblies for Drug Delivery: Designing Structures for Enhanced Drug Function
Block copolymers spontaneously assemble into nanoscaled polymeric micelles, which have significant potential as drug carriers. Following much work...